What it is
Normal red blood cells are disc-shaped and flexible enough to move through blood vessels.[1]
Why it matters
In sickle cell disease, red blood cells become misshaped because of a hemoglobin gene mutation and may not bend or move easily.[1]
What it affects
- Shape and flexibility connect hemoglobin biology to blocked blood flow, pain crises, stroke, lung, eye, kidney, and infection context.[1]
Interpretation traps
- BioConst does not interpret sickle trait, genotype, or treatment eligibility.[1]