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Medical Wiki

PTH

Parathyroid hormone: a calcium-phosphate control signal that must be read with calcium and kidney context.

What it is

PTH is a hormone from the parathyroid glands that helps regulate blood calcium and phosphate.[1,2]

Why it matters

It links blood calcium, phosphate, vitamin D, kidney function, and bone remodeling.[1,3]

What it affects

  • High PTH with high calcium suggests a different context from high PTH with low or normal calcium.[1]
  • Chronic kidney disease can change PTH, phosphate, calcium, vitamin D metabolism, and bone turnover together.[3]

Interpretation traps

  • PTH is high-risk for self-interpretation; same-draw calcium, kidney function, vitamin D, medicines, and lab method matter.[1]

Related conditions

Hyperparathyroid bone diseaseCKD-mineral and bone disorder / renal osteodystrophyOsteomalacia and rickets