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Medical Wiki

Serum calcium

Blood calcium is tightly regulated and does not directly tell how much calcium is in bone.

What it is

A calcium blood test measures calcium in blood, where only a small portion of body calcium is found.^[1]

Why it matters

Blood calcium helps interpret parathyroid, kidney, vitamin D, and cancer-related contexts, but it is not a bone calcium score.^[1,2]

What it affects

High blood calcium can be related to parathyroid disorders, certain cancers, Paget disease, excessive vitamin D exposure, or other conditions.^[1]
Low blood calcium can be related to low vitamin D, kidney disease, parathyroid problems, low protein, or other contexts.^[1]

Interpretation traps

Total calcium and ionized calcium are different measurements; albumin, illness, supplements, and medicines can affect interpretation.^[1]

Related conditions

Hyperparathyroid bone disease CKD-mineral and bone disorder / renal osteodystrophy Osteomalacia and rickets Bone tumors and metastatic bone disease Myeloma bone disease