これは何か
Tau normally helps stabilize microtubules, but abnormal changes in Alzheimer disease can lead tau to form tangles inside neurons.[1]
なぜ重要か
Tau tangles can interfere with neuronal transport systems and synaptic communication.[1]
どの判断に影響するか
- Abnormal tau tends to accumulate in memory-related brain regions and can spread as Alzheimer disease progresses.[1]
解釈上の注意
- Alzheimer disease is not only tau or only amyloid; NIA describes a complex interplay among tau, beta-amyloid, and other factors.[1]