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Tau

A microtubule-related protein that can form neurofibrillary tangles in Alzheimer disease.

這是什麼

Tau normally helps stabilize microtubules, but abnormal changes in Alzheimer disease can lead tau to form tangles inside neurons.[1]

為什麼重要

Tau tangles can interfere with neuronal transport systems and synaptic communication.[1]

它會影響哪些判斷

  • Abnormal tau tends to accumulate in memory-related brain regions and can spread as Alzheimer disease progresses.[1]

解讀陷阱

  • Alzheimer disease is not only tau or only amyloid; NIA describes a complex interplay among tau, beta-amyloid, and other factors.[1]

相關病症